Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ATIC | P31939 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16015147 | 0.85 | KMT2A (0.48) | KMT2AALDH1A1MEN1GAAKDM4E | |
| SCHEMBL12960523 | 0.81 | L3MBTL1 (0.51) | KMT2AALDH1A1MEN1GAAKDM4E | |
| SCHEMBL17491050 | 0.80 | GAA (0.61) | KMT2AALDH1A1MEN1GAAKDM4E | |
| SCHEMBL7527649 | 0.80 | KMT2A (0.53) | KMT2AALDH1A1MEN1GAAKDM4E | |
| SCHEMBL1813969 | 0.80 | TDP1 (0.43) | KMT2AALDH1A1MEN1GAAKDM4E | |
| SCHEMBL1811889 | 0.80 | TGM2 (0.50) | KMT2AALDH1A1MEN1GAAKDM4E | |
| SCHEMBL13904604 | 0.79 | GAA (0.51) | KMT2AALDH1A1MEN1GAAKDM4E | |
| SCHEMBL28199608 | 0.77 | GAA (0.50) | KMT2AALDH1A1MEN1GAAKDM4E | |
| SCHEMBL6362762 | 0.77 | POLB (0.48) | KMT2AALDH1A1MEN1GAAKDM4E | |
| SCHEMBL7297478 | 0.77 | CA1 (0.50) | GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012157782-A1 | TONER | CANON KABUSHIKI KAISHA (JP) | 2012-11-22 | — | — | WO | disclosed |