Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.37 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386968 | 0.89 | MEN1 (0.37) | TRPM8SLC2A1MGLLMEN1LMNA | |
| SCHEMBL1397545 | 0.89 | CCR9 (0.34) | CCR9MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL1397829 | 0.88 | CCR9 (0.36) | SLC2A1CCR9FLT3 | |
| SCHEMBL20768023 | 0.87 | SLC2A1 (0.38) | TRPM8CDK8SLC2A1MGLLMEN1 | |
| SCHEMBL1397553 | 0.86 | TRPM8 (0.35) | TRPM8CDK8SLC2A1MGLLMEN1 | |
| SCHEMBL1397688 | 0.86 | TRPM8 (0.34) | TRPM8CDK8SLC2A1MGLLCETP | |
| SCHEMBL1386856 | 0.83 | PPARG (0.35) | SLC2A1MGLLCETPLMNAHDAC8 | |
| SCHEMBL1397717 | 0.82 | MCL1 (0.34) | CDK8SLC2A1MGLLMEN1LMNA | |
| SCHEMBL1397658 | 0.80 | TRPM8 (0.37) | TRPM8SLC2A1CCR9CETPHDAC8 | |
| SCHEMBL1386237 | 0.79 | ESRRG (0.34) | TRPM8HDAC8HDAC11HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007726-B1 | BENZAMIDE AND HETEROARENE DERIVATIVES AS CETP INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-03-02 | — | — | EP | disclosed |