Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | TACR3 | P29371 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386433 | 0.95 | TRPV1 (0.35) | ESRRGTP53MAPTLPAR1LPAR5 | |
| SCHEMBL1385947 | 0.90 | ESRRG (0.36) | ESRRGTP53MAPTHDAC6HDAC8 | |
| SCHEMBL1386968 | 0.89 | MEN1 (0.37) | ESRRGTP53MAPTLPAR1LPAR5 | |
| SCHEMBL5527991 | 0.83 | PTPN7 (0.36) | ESRRGTP53MAPTPTPN7DUSP3 | |
| SCHEMBL5528458 | 0.83 | GRM5 (0.38) | ESRRGTP53MAPTPTPN7DUSP3 | |
| SCHEMBL1385936 | 0.83 | LPAR1 (0.37) | ESRRGTP53MAPTLPAR1LPAR5 | |
| SCHEMBL1386856 | 0.81 | PPARG (0.35) | HDAC6HDAC8HDAC11 | |
| SCHEMBL5530729 | 0.81 | NR3C2 (0.39) | ESRRGTP53MAPTPTPN7DUSP3 | |
| SCHEMBL1386801 | 0.81 | SIGMAR1 (0.32) | ESRRGTP53MAPT | |
| SCHEMBL12521098 | 0.81 | TRPM8 (0.38) | ESRRGTP53MAPTPTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4787254-B2 | — | — | 2011-10-05 | — | — | JP | claimed |