Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807249 | 1.00 | CTSB (0.36) | CTSBTSHRGPR139TDP1SLC6A2 | |
| SCHEMBL4808176 | 1.00 | CTSB (0.36) | CTSBTSHRGPR139TDP1SLC6A2 | |
| SCHEMBL4003598 | 0.92 | CTSB (0.39) | CTSBTSHRGPR139TDP1SLC6A2 | |
| SCHEMBL13985455 | 0.85 | KMO (0.40) | CTSBSLC6A4SLC6A3L3MBTL1ALDH1A1 | |
| SCHEMBL4014499 | 0.78 | MAPT (0.38) | TDP1HPGDL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4809892 | 0.77 | ALDH1A1 (0.37) | TDP1L3MBTL1ALDH1A1TP53KCNA5 | |
| SCHEMBL13980101 | 0.77 | ALDH1A1 (0.37) | TDP1L3MBTL1ALDH1A1TP53KCNA5 | |
| SCHEMBL4809141 | 0.77 | ALDH1A1 (0.37) | TDP1L3MBTL1ALDH1A1TP53KCNA5 | |
| SCHEMBL13985456 | 0.76 | KMO (0.45) | SLC6A4SLC6A3L3MBTL1ALDH1A1 | |
| SCHEMBL4806559 | 0.68 | TDP1 (0.38) | TDP1L3MBTL1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465808-B2 | CCK-1 receptor modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-12-16 | — | — | US | disclosed |