Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985455 | 0.91 | KMO (0.40) | KMOL3MBTL1SLC6A4SLC6A3MEN1 | |
| SCHEMBL4003598 | 0.83 | CTSB (0.39) | L3MBTL1SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL4807273 | 0.78 | ALDH1A1 (0.42) | L3MBTL1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL4808176 | 0.76 | CTSB (0.36) | L3MBTL1SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL13980100 | 0.76 | CTSB (0.36) | L3MBTL1SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL4807249 | 0.76 | CTSB (0.36) | L3MBTL1SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL7632409 | 0.74 | FFAR1 (0.52) | SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL436605 | 0.73 | KMO (0.56) | KMOSLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL3678015 | 0.72 | KMO (0.63) | KMOMEN1KMT2A | |
| SCHEMBL728115 | 0.72 | KMO (0.63) | KMOMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465808-B2 | CCK-1 receptor modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-12-16 | — | — | US | disclosed |