Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886396 | 0.76 | CNR2 (0.45) | — | |
| SCHEMBL3890975 | 0.74 | HPGD (0.41) | MEN1KMT2ASIGMAR1BRD4LMNA | |
| SCHEMBL13871330 | 0.69 | POLB (0.49) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL300348 | 0.68 | POLB (0.49) | MEN1KMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL14003128 | 0.67 | P2RX7 (0.46) | MEN1KMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL300505 | 0.67 | SIGMAR1 (0.46) | MEN1KMT2ASIGMAR1SMYD3BRD4 | |
| SCHEMBL14003141 | 0.67 | SIGMAR1 (0.46) | MEN1KMT2ASIGMAR1SMYD3BRD4 | |
| SCHEMBL14003143 | 0.67 | SIGMAR1 (0.46) | MEN1KMT2ASIGMAR1SMYD3BRD4 | |
| SCHEMBL4709016 | 0.67 | CNR2 (0.40) | — | |
| SCHEMBL4712108 | 0.66 | TDP1 (0.43) | MEN1KMT2ATDP1LMNACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863479-B1 | TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS CROSS REFERENCE TO RELATED APPLICATIONS | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-10 | — | — | EP | disclosed |