Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934766 | 0.78 | GSK3B (0.53) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL13980506 | 0.76 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL3922719 | 0.76 | HSD17B10 (0.69) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL8636638 | 0.73 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL15488927 | 0.72 | KLF10 (0.60) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL457954 | 0.71 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL13461466 | 0.71 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL9057785 | 0.70 | L3MBTL1 (0.72) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL31040323 | 0.70 | L3MBTL1 (0.72) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL4914396 | 0.70 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458700-B1 | SUBSTITUTED 2-PHENYL BENZOFURANS AS ESTROGENIC AGENTS | WYETH CORP (US) | 2008-12-03 | — | — | EP | disclosed |