Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689996 | 0.93 | CYP3A4 (0.33) | MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL13980640 | 0.80 | KMT2A (0.34) | MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL4688248 | 0.78 | PGR (0.31) | LMNATHRB | |
| SCHEMBL4687511 | 0.73 | PLA2G2A (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL14088961 | 0.73 | ATM (0.39) | LMNAKMT2ACYP3A4ALDH1A1 | |
| SCHEMBL13980679 | 0.72 | CCR6 (0.38) | — | |
| SCHEMBL4688246 | 0.69 | ALDH1A1 (0.34) | LMNAMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL4691042 | 0.69 | ALDH1A1 (0.36) | MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL1935987 | 0.68 | ALDH1A1 (0.46) | KMT2AHPGDCYP3A4ALDH1A1PARP10 | |
| SCHEMBL3911151 | 0.68 | LMNA (0.47) | LMNAMEN1KMT2ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443046-B1 | NOVEL 4-(2FUROYL)AMINOPIPERIDINES, INTERMEDIATES IN SYNTHESIZING THE SAME, PROCESS FOR PRODUCING THE SAME AND MEDICINAL USE OF THE SAME | KYORIN SEIYAKU KK (JP) | 2008-12-17 | — | — | EP | disclosed |