Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 7/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982203 | 0.90 | LMNA (0.35) | PTGESEPHX2LMNA | |
| SCHEMBL3029330 | 0.88 | CYP3A4 (0.40) | PTGESDDR1TLR8EPHX2TP53 | |
| SCHEMBL13982190 | 0.87 | PTGES (0.36) | PTGESLMNA | |
| SCHEMBL13982250 | 0.86 | PTGES (0.38) | PTGESDDR1TLR8EPHX2NR1H4 | |
| SCHEMBL13982112 | 0.85 | DDR1 (0.35) | PTGESDDR1TLR8EPHX2NR1H4 | |
| SCHEMBL13982188 | 0.85 | EPHX2 (0.36) | PTGESDDR1EPHX2NR1H4LMNA | |
| SCHEMBL13217776 | 0.85 | TLR8 (0.40) | PTGESDDR1TLR8EPHX2NR1H4 | |
| SCHEMBL13982214 | 0.83 | LMNA (0.36) | PTGESEPHX2NR1H4LMNAP2RX7 | |
| SCHEMBL13982216 | 0.83 | P2RX7 (0.35) | PTGESEPHX2LMNAP2RX7 | |
| SCHEMBL13982267 | 0.83 | AKR1B1 (0.33) | PTGESEPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154271-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |