SCHEMBL1398237

SCHEMBL1398237

C=CC(=O)n1ccc(=O)[nH]c1=O

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.42
DDB1 Q16531 1/20 0.39
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
DUT P33316 2/20 0.33
PKM P14618 1/20 0.33
GSK3B P49841 1/20 0.32
SLC28A1 O00337 1/20 0.32
SLC28A2 O43868 1/20 0.32
SLC29A1 Q99808 1/20 0.32
SLC28A3 Q9HAS3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20365469 0.82 CRBN (0.44) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL10953746 0.78 CRBN (0.50) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL27581645 0.78 CRBN (0.50) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL2976955 0.76 CRBN (0.48) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL7056290 0.75 CRBN (0.52) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL4755093 0.75 CRBN (0.52) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL28132697 0.75 CRBN (0.47) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL1526612 0.74 CRBN (0.47) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL7559284 0.74 CYP3A4 (0.39) CRBNALDH1A1LMNADUTPKM
SCHEMBL24755086 0.73 CRBN (0.50) CRBNDDB1ALDH1A1LMNADUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113413483-B Adhesive-non-adhesive integrated hydrogel, preparation method thereof and application thereof in wound repair 四川大学 2022-07-05 CN claimed
CN-113413483-A Adhesive-non-adhesive integrated hydrogel, preparation method thereof and application thereof in wound repair 四川大学 2021-09-21 CN claimed
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP claimed
EP-2764065-A1 SACRIFICIAL ADHESIVE COATINGS Rochal Industries, LLP (US) 2014-08-13 EP claimed
WO-2013052276-A1 SACRIFICIAL ADHESIVE COATINGS ROCHAL INDUSTRIES, LLP (US) 2013-04-11 WO claimed
US-8263720-B1 Sacrificial adhesive coatings ROCHAL INDUSTRIES, LLP (US) 2012-09-11 US claimed
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same ROCHAL TECHNOLOGIES LLC (US) 2023-12-12 US disclosed
CN-113413483-B Adhesive-non-adhesive integrated hydrogel, preparation method thereof and application thereof in wound repair 四川大学 2022-07-05 CN disclosed
CN-113413483-A Adhesive-non-adhesive integrated hydrogel, preparation method thereof and application thereof in wound repair 四川大学 2021-09-21 CN disclosed
EP-3220741-B1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME ROCHAL IND LLC (US) 2021-02-24 EP disclosed
US-20170360825-A1 Composition and Kits for Inhibition of Pathogenic Microbial Infection and Methods of Using the Same ROCHAL INDUSTRIES, LLC (US) 2017-12-21 US disclosed
EP-3220741-A1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME Rochal Industries, LLC (US) 2017-09-27 EP disclosed
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP disclosed
WO-2013052276-A1 SACRIFICIAL ADHESIVE COATINGS ROCHAL INDUSTRIES, LLP (US) 2013-04-11 WO disclosed
US-8263720-B1 Sacrificial adhesive coatings ROCHAL INDUSTRIES, LLP (US) 2012-09-11 US disclosed
EP-1968655-B1 CONFORMABLE BANDAGE AND COATING MATERIAL ROCHAL IND LLP (US) 2011-03-02 EP disclosed
US-7795326-B2 Solution of an amphiphilic copolymer of a nitrogen-containing monomer, such as N-isopropylacrylamide, and a siloxy monomer, preferably 3-(methacryloyloxy)propyltris(trimethylsiloxy)silane in non-stinging, volatile, siloxane, alkane, fluorocarbon, lor iquid or supercritical carbon dioxide; medical devices ROCHAL INDUSTRIES, LLP (US) 2010-09-14 US disclosed
EP-1968655-A2 CONFORMABLE BANDAGE AND COATING MATERIAL Rochal Industries, LLP (US) 2008-09-17 EP disclosed
WO-2007067866-A2 CONFORMABLE BANDAGE AND COATING MATERIAL ROCHAL INDUSTRIES, LLP (US) 2007-06-14 WO disclosed
US-20070129474-A1 Solution of an amphiphilic copolymer of a nitrogen-containing monomer, such as N-isopropylacrylamide, and a siloxy monomer, preferably 3-(methacryloyloxy)propyltris(trimethylsiloxy)silane in non-stinging, volatile, siloxane, alkane, fluorocarbon, lor iquid or supercritical carbon dioxide; medical devices ROCHAL INDUSTRIES, LLP. (US) 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170360825-A1 Composition and Kits for Inhibition of Pathogenic Microbial Infection and Methods of Using the Same CUTA, MMP8, MMP1 CRBN 4054/4885DDB1 858/4885ALDH1A1 4110/4885
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same CUTA, MMP8, MMP1 CRBN 4054/4885DDB1 858/4885ALDH1A1 4110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.