SCHEMBL4755093

SCHEMBL4755093

CC(=O)n1ccc(=O)[nH]c1=O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.52
DDB1 Q16531 1/20 0.42
NOTUM Q6P988 3/20 0.41
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
DUT P33316 3/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10953746 0.83 CRBN (0.50) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL24755086 0.82 CRBN (0.50) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL11582823 0.82 CRBN (0.41) CRBNDDB1NOTUMALDH1A1
SCHEMBL5353434 0.81 CRBN (0.46) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL2976955 0.81 CRBN (0.48) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL1526612 0.79 CRBN (0.47) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL5811343 0.78 CRBN (0.43) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL108176 0.78 CRBN (0.46) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL1398237 0.75 CRBN (0.42) CRBNDDB1ALDH1A1LMNADUT
SCHEMBL8988100 0.73 CRBN (0.45) CRBNDDB1ALDH1A1LMNADUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302995-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF SHIVALILA CHIKDU SHAKTI (US) 2025-10-02 US disclosed
US-20250262235-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD (SG) 2025-08-21 US disclosed
WO-2025072862-A9 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2025-06-26 WO disclosed
US-20250135036-A1 COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2025-05-01 US disclosed
EP-4522744-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2025-03-19 EP disclosed
EP-4507700-A2 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO Wave Life Sciences Ltd. (SG) 2025-02-19 EP disclosed
CN-119452084-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2025-02-14 CN disclosed
CN-119317632-A Oligonucleotide compositions and methods relating thereto 波涛生命科学有限公司 2025-01-14 CN disclosed
EP-4404942-A2 COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2024-07-31 EP disclosed
US-20240026358-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2024-01-25 US disclosed
WO-1996011205-A1 PEPTIDE NUCLEIC ACID CONJUGATES ISIS PHARMACEUTICALS, INC. (US) 1996-04-18 WO disclosed
EP-0068268-B1 ENHANCER OF ANTI-TUMOUR EFFECT Yamasa Shoyu Kabushiki Kaisha (JP) 1985-05-02 EP disclosed
EP-0048022-B1 ENHANCER OF ANTI-TUMOR EFFECT Yamasa Shoyu Kabushiki Kaisha (JP) 1985-01-09 EP disclosed
US-4434788-A 3'-DEOXYGUANOSINE OR 3'-DEOXYURIDINE ADMINISTERED WITH RADIATION YAMASA SHOYU KABUSHIKI KAISHA (JP) 1984-03-06 US disclosed
US-4432348-A 3'-DEOXYGUANOSINE-5'-MONOPHOSPHATE OR 3'-DEOXYADENOSINE-5'-MONOPHOSPHATE YAMASA SHOYU KABUSHIKI KAISHA (JP) 1984-02-21 US disclosed
EP-0045944-B1 ENHANCER OF ANTI-TUMOR EFFECT Yamasa Shoyu Kabushiki Kaisha (JP) 1983-08-31 EP disclosed
EP-0079054-A1 Enhancer of antitumor effect Yamasa Shoyu Kabushiki Kaisha (JP) 1983-05-18 EP disclosed
EP-0068268-A1 Enhancer of anti-tumour effect Yamasa Shoyu Kabushiki Kaisha (JP) 1983-01-05 EP disclosed
EP-0048022-A2 Enhancer of anti-tumor effect Yamasa Shoyu Kabushiki Kaisha (JP) 1982-03-24 EP disclosed
EP-0045944-A1 Enhancer of anti-tumor effect Yamasa Shoyu Kabushiki Kaisha (JP) 1982-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302995-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF ADAR, NSUN2, RNGTT CRBN 1532/4885DDB1 571/4885NOTUM 3265/4885
US-20250262235-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO ADAR, RNGTT, NSUN2 CRBN 3399/4885DDB1 539/4885NOTUM 1911/4885
US-20250135036-A1 COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF MECP2, ADAR, NSUN2 CRBN 174/4885DDB1 621/4885NOTUM 4697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.