SCHEMBL1398292

SCHEMBL1398292

C=CC(=O)Nc1nc2nc[nH]c2c(=O)[nH]1

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 0.68
XDH P47989 3/20 0.50
PNP P00491 1/20 0.48
POLA1 P09884 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29411658 0.82 GDA (0.76) GDAXDHPNPPOLA1
SCHEMBL6821775 0.81 GDA (0.74) GDAXDHPNPPOLA1
SCHEMBL30510976 0.81 GDA (0.74) GDAXDHPNPPOLA1
SCHEMBL219478 0.81 GDA (1.00) GDAXDHPNPPOLA1
SCHEMBL19466100 0.80 GDA (0.76) GDAXDHPNPPOLA1
Hypoxanthine SCHEMBL27727730 0.80 GDA (0.72) GDAXDHPNPPOLA1
SCHEMBL30901353 0.80 GDA (0.58) GDAXDHPNPPOLA1
SCHEMBL28559767 0.80 GDA (0.75) GDAXDHPNPPOLA1
SCHEMBL9581457 0.80 GDA (0.89) GDAXDHPNPPOLA1
SCHEMBL31093422 0.79 GDA (0.74) GDAXDHPNPPOLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113413483-B Adhesive-non-adhesive integrated hydrogel, preparation method thereof and application thereof in wound repair 四川大学 2022-07-05 CN claimed
CN-113413483-A Adhesive-non-adhesive integrated hydrogel, preparation method thereof and application thereof in wound repair 四川大学 2021-09-21 CN claimed
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP claimed
EP-2764065-A1 SACRIFICIAL ADHESIVE COATINGS Rochal Industries, LLP (US) 2014-08-13 EP claimed
WO-2013052276-A1 SACRIFICIAL ADHESIVE COATINGS ROCHAL INDUSTRIES, LLP (US) 2013-04-11 WO claimed
US-8263720-B1 Sacrificial adhesive coatings ROCHAL INDUSTRIES, LLP (US) 2012-09-11 US claimed
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same ROCHAL TECHNOLOGIES LLC (US) 2023-12-12 US disclosed
CN-113413483-B Adhesive-non-adhesive integrated hydrogel, preparation method thereof and application thereof in wound repair 四川大学 2022-07-05 CN disclosed
CN-113413483-A Adhesive-non-adhesive integrated hydrogel, preparation method thereof and application thereof in wound repair 四川大学 2021-09-21 CN disclosed
EP-3220741-B1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME ROCHAL IND LLC (US) 2021-02-24 EP disclosed
US-20170360825-A1 Composition and Kits for Inhibition of Pathogenic Microbial Infection and Methods of Using the Same ROCHAL INDUSTRIES, LLC (US) 2017-12-21 US disclosed
EP-3220741-A1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME Rochal Industries, LLC (US) 2017-09-27 EP disclosed
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP disclosed
WO-2013052276-A1 SACRIFICIAL ADHESIVE COATINGS ROCHAL INDUSTRIES, LLP (US) 2013-04-11 WO disclosed
US-8263720-B1 Sacrificial adhesive coatings ROCHAL INDUSTRIES, LLP (US) 2012-09-11 US disclosed
EP-1968655-B1 CONFORMABLE BANDAGE AND COATING MATERIAL ROCHAL IND LLP (US) 2011-03-02 EP disclosed
US-7795326-B2 Solution of an amphiphilic copolymer of a nitrogen-containing monomer, such as N-isopropylacrylamide, and a siloxy monomer, preferably 3-(methacryloyloxy)propyltris(trimethylsiloxy)silane in non-stinging, volatile, siloxane, alkane, fluorocarbon, lor iquid or supercritical carbon dioxide; medical devices ROCHAL INDUSTRIES, LLP (US) 2010-09-14 US disclosed
EP-1968655-A2 CONFORMABLE BANDAGE AND COATING MATERIAL Rochal Industries, LLP (US) 2008-09-17 EP disclosed
WO-2007067866-A2 CONFORMABLE BANDAGE AND COATING MATERIAL ROCHAL INDUSTRIES, LLP (US) 2007-06-14 WO disclosed
US-20070129474-A1 Solution of an amphiphilic copolymer of a nitrogen-containing monomer, such as N-isopropylacrylamide, and a siloxy monomer, preferably 3-(methacryloyloxy)propyltris(trimethylsiloxy)silane in non-stinging, volatile, siloxane, alkane, fluorocarbon, lor iquid or supercritical carbon dioxide; medical devices ROCHAL INDUSTRIES, LLP. (US) 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170360825-A1 Composition and Kits for Inhibition of Pathogenic Microbial Infection and Methods of Using the Same CUTA, MMP8, MMP1 GDA 3244/4885XDH 4133/4885PNP 630/4885
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same CUTA, MMP8, MMP1 GDA 3244/4885XDH 4133/4885PNP 630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.