Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD4 | P01730 | 16/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10224252 | 0.79 | HDAC6 (0.47) | CD4 | |
| SCHEMBL4751184 | 0.76 | KDM4E (0.52) | CD4PKMALDH1A1 | |
| SCHEMBL14751054 | 0.75 | AKR1C3 (0.65) | CD4PKMALDH1A1POLBHTT | |
| Ammonia Solution, Strong SCHEMBL4811566 | 0.75 | KDM4E (0.51) | CD4PKMALDH1A1 | |
| SCHEMBL20389256 | 0.74 | AKR1C3 (0.60) | CD4PKM | |
| SCHEMBL13302259 | 0.74 | KMT2A (0.77) | PKMALDH1A1POLB | |
| SCHEMBL19104717 | 0.73 | CD4 (0.52) | CD4PKMALDH1A1POLBHTT | |
| SCHEMBL265611 | 0.71 | PKM (0.61) | CD4PKMALDH1A1POLBHTT | |
| SCHEMBL12330050 | 0.71 | PKM (0.61) | CD4PKMALDH1A1POLBHTT | |
| SCHEMBL5632531 | 0.71 | AKR1C3 (0.60) | CD4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149163-A2 | POTASSIUM ION CHANNEL MODULATORS AND USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |