Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KCNA1 | Q09470 | 3/20 | 0.48 |
| ▸ | KCNAB1 | Q14722 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CD4 | P01730 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL4811566 | 0.99 | KDM4E (0.51) | KDM4EKCNA1KCNAB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4753300 | 0.87 | ALDH1A1 (0.45) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL13983989 | 0.86 | KCNA1 (0.66) | KDM4EKCNA1KCNAB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4753275 | 0.84 | KCNA1 (0.53) | KDM4EKCNA1KCNAB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4753834 | 0.82 | KCNA1 (0.51) | KDM4EKCNA1KCNAB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4753862 | 0.78 | KCNA1 (0.65) | KDM4EKCNA1KCNAB1ALDH1A1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL4753298 | 0.78 | CA1 (0.43) | KDM4EALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL4752355 | 0.78 | KCNA1 (0.49) | KDM4EKCNA1KCNAB1ALDH1A1LMNA | |
| SCHEMBL10224252 | 0.77 | HDAC6 (0.47) | SMN1; SMN2LMNAMAPTCD4 | |
| SCHEMBL13983878 | 0.76 | CD4 (0.51) | ALDH1A1PKMCD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149163-A2 | POTASSIUM ION CHANNEL MODULATORS AND USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008149163-A2 | POTASSIUM ION CHANNEL MODULATORS AND USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |