Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13267170 | 0.91 | HRH3 (0.50) | — | |
| SCHEMBL13984527 | 0.79 | ACHE (0.50) | ACHE | |
| SCHEMBL3012858 | 0.77 | — | — | |
| SCHEMBL3015924 | 0.76 | KMT2A (0.57) | — | |
| SCHEMBL19534355 | 0.71 | HRH3 (0.54) | — | |
| SCHEMBL3022978 | 0.70 | MMP2 (0.52) | — | |
| SCHEMBL13244730 | 0.70 | LMNA (0.51) | — | |
| SCHEMBL18023372 | 0.70 | KMT2A (0.41) | — | |
| SCHEMBL13244556 | 0.70 | HRH3 (0.56) | — | |
| SCHEMBL3014437 | 0.69 | SMN1; SMN2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2662353-A2 | Antibacterial agents | Achaogen, Inc. (US) | 2013-11-13 | — | — | EP | disclosed |
| WO-2008154642-A2 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2008-12-18 | — | — | WO | disclosed |