Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3015924 | 0.85 | KMT2A (0.57) | KMT2A | |
| SCHEMBL13267211 | 0.76 | KMT2A (0.60) | KMT2A | |
| SCHEMBL28162775 | 0.75 | KMT2A (0.58) | KMT2A | |
| SCHEMBL28162774 | 0.71 | KMT2A (0.56) | KMT2A | |
| SCHEMBL13984656 | 0.70 | ACHE (0.47) | — | |
| SCHEMBL3012858 | 0.70 | — | — | |
| SCHEMBL3017442 | 0.69 | KMT2A (0.65) | KMT2AMMP2MMP8MMP13 | |
| SCHEMBL26096917 | 0.67 | ALDH1A1 (0.62) | MMP2MMP8MMP13 | |
| SCHEMBL19534355 | 0.66 | HRH3 (0.54) | MMP2MMP8MMP13 | |
| SCHEMBL3018975 | 0.66 | ALDH1A1 (0.54) | KMT2AMMP2MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170814-B1 | ANTIBACTERIAL AGENTS | ACHAOGEN INC (US) | 2016-08-17 | — | — | EP | disclosed |