Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15849842 | 0.78 | MAPT (0.56) | MAPTALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL13941618 | 0.78 | FAAH (0.48) | MAPTALDH1A1POLBFAAHMGLL | |
| SCHEMBL13985158 | 0.77 | EGFR (0.64) | MAPTALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL15897789 | 0.76 | BCHE (0.74) | MAPTALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL17453758 | 0.76 | MAPT (0.68) | MAPTALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL31054222 | 0.75 | NPC1 (0.69) | MAPTALDH1A1RAB9ANPC1TAAR1 | |
| SCHEMBL13941446 | 0.74 | FAAH (0.52) | MAPTALDH1A1POLBFAAHMGLL | |
| SCHEMBL16275220 | 0.73 | PLK4 (0.55) | MAPTALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL13985286 | 0.72 | MAPT (0.55) | MAPTALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL13941428 | 0.72 | FAAH (0.54) | MAPTALDH1A1POLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155675-B1 | KINASE INHIBITORS, COMPOSITIONS THEREOF, AND METHODS OF USE THEREWITH | PROVID PHARMACEUTICALS INC (US) | 2014-02-19 | — | — | EP | disclosed |
| WO-2008156573-A1 | KINASE INHIBITORS, COMPOSITIONS THEREOF, AND METHODS OF USE THEREWITH | PROVID PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |