Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985285 | 0.80 | PLK4 (0.57) | KMT2AFAAHMGLLMEN1 | |
| SCHEMBL15849842 | 0.77 | MAPT (0.56) | MAPTRAB9ANPC1TAAR1SMN1; SMN2 | |
| SCHEMBL31054222 | 0.76 | NPC1 (0.69) | MAPTRAB9ANPC1TAAR1SMN1; SMN2 | |
| SCHEMBL1719786 | 0.72 | RAB9A (1.00) | MAPTRAB9ANPC1TAAR1SMN1; SMN2 | |
| SCHEMBL13985114 | 0.72 | MAPT (0.54) | MAPTRAB9ANPC1TAAR1SMN1; SMN2 | |
| SCHEMBL17453758 | 0.71 | MAPT (0.68) | MAPTRAB9ANPC1TAAR1SMN1; SMN2 | |
| SCHEMBL15897789 | 0.71 | BCHE (0.74) | MAPTRAB9ANPC1KMT2AFAAH | |
| SCHEMBL13985290 | 0.71 | CA12 (0.56) | MAPTRAB9ANPC1TAAR1SMN1; SMN2 | |
| SCHEMBL13941428 | 0.70 | FAAH (0.54) | MAPTRAB9ANPC1TAAR1SMN1; SMN2 | |
| SCHEMBL11059378 | 0.70 | SMN1; SMN2 (0.94) | MAPTRAB9ANPC1TAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156573-A1 | KINASE INHIBITORS, COMPOSITIONS THEREOF, AND METHODS OF USE THEREWITH | PROVID PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |