Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955986 | 0.94 | MCL1 (0.53) | MCL1DHFRNPC1RAB9AMAPT | |
| SCHEMBL3625528 | 0.87 | NPC1 (0.52) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL10135453 | 0.86 | MLYCD (0.50) | MCL1DHFRNPC1RAB9AMAPT | |
| SCHEMBL2271509 | 0.84 | TSHR (0.52) | DHFRNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL13488787 | 0.84 | MCL1 (0.47) | MCL1DHFRNPC1RAB9AMAPT | |
| SCHEMBL23506932 | 0.81 | MCL1 (0.45) | MCL1DHFRNPC1RAB9AMAPT | |
| SCHEMBL13985068 | 0.81 | MCL1 (0.45) | MCL1DHFRNPC1RAB9AMAPT | |
| SCHEMBL19480532 | 0.80 | KIF11 (0.52) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL13488797 | 0.79 | BCHE (0.42) | NPC1RAB9AALDH1A1PTGIRTSHR | |
| SCHEMBL779443 | 0.79 | NPC1 (0.58) | NPC1RAB9AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009003029-A2 | HIGH-TEMPERATURE SPIN-ON TEMPORARY BONDING COMPOSITIONS | BREWER SCIENCE INC. (US) | 2008-12-31 | — | — | WO | disclosed |