Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955986 | 0.90 | MCL1 (0.53) | MCL1DHFRNPC1RAB9AMAPT | |
| SCHEMBL11539224 | 0.88 | NPC1 (0.48) | NPC1RAB9AMAPTESR1ESR2 | |
| SCHEMBL23506932 | 0.85 | MCL1 (0.45) | MCL1DHFRNPC1RAB9AMAPT | |
| SCHEMBL13985235 | 0.84 | MCL1 (0.49) | MCL1DHFRNPC1RAB9AMAPT | |
| SCHEMBL13488797 | 0.84 | BCHE (0.42) | NPC1RAB9AKIF11LMNATP53 | |
| SCHEMBL10135453 | 0.82 | MLYCD (0.50) | MCL1DHFRNPC1RAB9AMAPT | |
| SCHEMBL24865852 | 0.82 | NPC1 (0.44) | NPC1RAB9AMAPTESR1ESR2 | |
| SCHEMBL18159470 | 0.81 | TP53 (0.48) | LMNATP53RXFP1MAPK1ATM | |
| SCHEMBL576175 | 0.81 | TP53 (0.48) | LMNATP53RXFP1MAPK1ATM | |
| SCHEMBL22653014 | 0.79 | BCHE (0.39) | NPC1RAB9AKIF11LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036136-A1 | Maleimide Containing Ester and Sulfide Functionalities | HENKEL AG & CO. KGAA (DE) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036136-A1 | Maleimide Containing Ester and Sulfide Functionalities | EPCAM, ILK, TST | MCL1 2558/4885DHFR 2741/4885NPC1 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.