Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22653014 | 0.94 | BCHE (0.39) | BCHEACHEALDH1A1EPHX2NR1H4 | |
| SCHEMBL338386 | 0.87 | BCHE (0.52) | BCHEACHETSHRKCNH2TP53 | |
| SCHEMBL576175 | 0.84 | TP53 (0.48) | ALDH1A1TSHRL3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL2271509 | 0.84 | TSHR (0.52) | ALDH1A1PTGIRTSHRNPC1RAB9A | |
| SCHEMBL18159470 | 0.84 | TP53 (0.48) | ALDH1A1TSHRL3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL13488787 | 0.84 | MCL1 (0.47) | NPC1RAB9AKCNH2TP53KIF11 | |
| SCHEMBL18643754 | 0.80 | KIF11 (0.52) | BCHEACHETSHRNPC1RAB9A | |
| SCHEMBL13985235 | 0.79 | MCL1 (0.49) | ALDH1A1PTGIRTSHRNPC1RAB9A | |
| SCHEMBL16933906 | 0.78 | EGFR (0.42) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL19532057 | 0.78 | TSHR (0.46) | ALDH1A1PTGIRTSHRKIF11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036136-A1 | Maleimide Containing Ester and Sulfide Functionalities | HENKEL AG & CO. KGAA (DE) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036136-A1 | Maleimide Containing Ester and Sulfide Functionalities | EPCAM, ILK, TST | BCHE 3032/4885ACHE 740/4885ALDH1A1 1531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.