Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.83 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.83 |
| ▸ | USP2 | O75604 | 7/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.83 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.83 |
| ▸ | LMNA | P02545 | 5/20 | 0.83 |
| ▸ | CNR1 | P21554 | 3/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.83 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | AR | P10275 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019757 | 1.00 | PGR (0.83) | PGRNR3C1USP2CYP3A4HIF1A | |
| Alclometasone Dipropionate SCHEMBL13985345 | 0.91 | PGR (1.00) | PGRNR3C1USP2CYP3A4HIF1A | |
| Alclometasone Dipropionate SCHEMBL6833 | 0.91 | PGR (1.00) | PGRNR3C1USP2CYP3A4HIF1A | |
| Alclometasone Dipropionate SCHEMBL29459697 | 0.91 | PGR (1.00) | PGRNR3C1USP2CYP3A4HIF1A | |
| Alclometasone Dipropionate SCHEMBL13423590 | 0.91 | PGR (1.00) | PGRNR3C1USP2CYP3A4HIF1A | |
| Alclometasone Dipropionate SCHEMBL11047317 | 0.91 | PGR (1.00) | PGRNR3C1USP2CYP3A4HIF1A | |
| SCHEMBL13653198 | 0.90 | PGR (0.86) | PGRNR3C1USP2CYP3A4HIF1A | |
| SCHEMBL13524392 | 0.89 | PGR (0.84) | PGRNR3C1USP2CYP3A4HIF1A | |
| SCHEMBL13653208 | 0.88 | PGR (0.83) | PGRNR3C1USP2CYP3A4HIF1A | |
| SCHEMBL14339625 | 0.83 | NR3C1 (0.85) | PGRNR3C1USP2CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470724-B2 | Phosphonate compounds having immuno-modulatory activity | GILEAD SCIENCES, INC. (US) | 2008-12-30 | — | — | US | disclosed |