Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RRM1 | P23921 | 1/20 | 0.50 |
| ▸ | RRM2 | P31350 | 1/20 | 0.50 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | DDX3X | O00571 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985375 | 0.86 | RAB9A (0.62) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL13985372 | 0.86 | RAB9A (0.52) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL13985289 | 0.81 | MGLL (0.49) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL13985370 | 0.80 | NPC1 (0.64) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL13985373 | 0.79 | FAAH (0.63) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL17452430 | 0.78 | RRM1 (0.58) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL2949066 | 0.78 | RAB9A (0.59) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL13985294 | 0.77 | MAPT (0.45) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL889783 | 0.77 | PLK4 (0.47) | MGLL | |
| Hydrochloric Acid SCHEMBL9577859 | 0.77 | RAB9A (0.58) | KMT2ARAB9AMEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765802-B2 | Kinase inhibitors, compositions thereof, and methods of use therewith | PROVID PHARMACEUTICALS, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| WO-2008156573-A1 | KINASE INHIBITORS, COMPOSITIONS THEREOF, AND METHODS OF USE THEREWITH | PROVID PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |