Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14516990 | 0.81 | RAB9A (0.51) | RAB9AGRM1CYP11B2GRM5GAA | |
| SCHEMBL11562309 | 0.77 | RAB9A (0.48) | RAB9AGRM1CYP11B2GRM5GAA | |
| Ammonia Solution, Strong SCHEMBL11559116 | 0.76 | RAB9A (0.47) | RAB9AGRM1CYP11B2GRM5GAA | |
| SCHEMBL19214262 | 0.75 | ALDH1A1 (0.50) | RAB9AGRM1CYP11B2ALDH1A1HPGD | |
| SCHEMBL23507084 | 0.75 | MKNK1 (0.47) | RAB9AGRM1CYP11B2XDHPTGS2 | |
| SCHEMBL11562101 | 0.75 | RAB9A (0.46) | RAB9AGRM1CYP11B2GRM5GAA | |
| SCHEMBL11560437 | 0.75 | RAB9A (0.46) | RAB9AGRM1CYP11B2GRM5GAA | |
| SCHEMBL11563739 | 0.72 | GABRA2 (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1PTGS2 | |
| SCHEMBL11812198 | 0.72 | GRM1 (0.50) | RAB9AGRM1GRM5GAASMN1; SMN2 | |
| SCHEMBL11559004 | 0.70 | ALDH1A1 (0.49) | RAB9AGRM1CYP11B2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |