Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985680 | 0.90 | MAPT (0.38) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL3141368 | 0.73 | TOP2A (0.43) | ALDH1A1KDM4ELMNAMAPK1KMT2A | |
| SCHEMBL3047145 | 0.73 | PLA2G2A (0.46) | ALDH1A1KDM4ELMNAKMT2AMAPT | |
| SCHEMBL25682702 | 0.68 | TDP1 (0.57) | ALDH1A1LMNAKMT2AMAPTNPC1 | |
| SCHEMBL9631380 | 0.68 | TDP1 (0.47) | ALDH1A1KDM4ELMNAKMT2AMAPT | |
| SCHEMBL7533851 | 0.68 | MAPT (0.40) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL3034156 | 0.67 | PLA2G2A (0.48) | ALDH1A1KDM4ELMNAKMT2AMAPT | |
| SCHEMBL13223627 | 0.67 | TOP2A (0.50) | ALDH1A1KDM4ELMNAMAPK1KMT2A | |
| SCHEMBL28510365 | 0.66 | KMT2A (0.47) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL5663425 | 0.65 | LMNA (0.44) | ALDH1A1KDM4ELMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459284-B2 | Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2008-12-02 | — | — | US | disclosed |