Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HRAS | P01112 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141368 | 0.88 | TOP2A (0.43) | DHODHTDP1KMT2AKDM4EALDH1A1 | |
| SCHEMBL924047 | 0.80 | PLA2G2A (0.51) | PLA2G2ADHODHTACR3TDP1CASP3 | |
| SCHEMBL3034156 | 0.78 | PLA2G2A (0.48) | PLA2G2ADHODHTACR3TDP1CASP3 | |
| SCHEMBL7531961 | 0.78 | PLA2G2A (0.48) | PLA2G2ADHODHTACR3TDP1CASP3 | |
| SCHEMBL924517 | 0.78 | PRNP (0.39) | PLA2G2ADHODHPRNPCA1CA2 | |
| SCHEMBL4802002 | 0.77 | PLA2G2A (0.48) | PLA2G2ADHODHACHETDP1KMT2A | |
| SCHEMBL13223653 | 0.76 | TOP2A (0.49) | PLA2G2ADHODHPRNPTDP1KMT2A | |
| SCHEMBL13223651 | 0.76 | PLA2G2A (0.45) | PLA2G2ADHODHPRNPTACR3TDP1 | |
| SCHEMBL13985684 | 0.73 | ALDH1A1 (0.39) | DHODHTDP1KMT2AKDM4EALDH1A1 | |
| SCHEMBL923917 | 0.73 | MMP13 (0.55) | PLA2G2AACHECASP3KMT2ASENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1946108-B1 | HIGH QUANTUM YIELD ACRIDINIUM COMPOUNDS AND THEIR USES IN IMPROVING ASSAY SENSITIVITY | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2014-10-01 | — | — | EP | disclosed |
| US-7785904-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-08-31 | — | — | US | disclosed |
| EP-1946108-A2 | HIGH QUANTUM YIELD ACRIDINIUM COMPOUNDS AND THEIR USES IN IMPROVING ASSAY SENSITIVITY | Bayer Healthcare LLC (US) | 2008-07-23 | — | — | EP | disclosed |
| US-20080014660-A1 | High Quantum Yield Acridinium Compounds and Their Uses in Improving Assay Sensitivity | BAYER HEALTHCARE LLC | 2008-01-17 | — | — | US | disclosed |
| US-7309615-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS MEDICAL SOLUTIONS DIAGNOSTIC (US) | 2007-12-18 | — | — | US | disclosed |
| WO-2006130736-A2 | HIGH QUANTUM YIELD ACRIDINIUM COMPOUNDS AND THEIR USES IN IMPROVING ASSAY SENSITIVITY | SIEMENS MEDICAL SOLUTIONS DIAGNOSTICS (US) | 2006-12-07 | — | — | WO | disclosed |
| US-20050221390-A1 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | BAYER HEALTHCARE LLC (US) | 2005-10-06 | — | — | US | disclosed |