Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4851392 | 0.89 | — | — | |
| SCHEMBL4852316 | 0.87 | PDK1 (0.31) | HTR4PDK1PDK2PDK3PDK4 | |
| SCHEMBL6034762 | 0.81 | TNKS (0.30) | — | |
| Hydrochloric Acid SCHEMBL4851644 | 0.80 | KDM4E (0.30) | — | |
| SCHEMBL4857687 | 0.79 | PDK1 (0.31) | HTR4PDK1PDK2PDK3PDK4 | |
| SCHEMBL4858890 | 0.75 | LIPG (0.30) | — | |
| SCHEMBL4850669 | 0.74 | MAOB (0.35) | HTR4 | |
| SCHEMBL4855206 | 0.74 | ACHE (0.41) | ESR2 | |
| SCHEMBL4856377 | 0.74 | EPHX2 (0.34) | HTR4 | |
| SCHEMBL4857480 | 0.72 | ALDH1A1 (0.41) | PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |