Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 5/20 | 0.35 |
| ▸ | WNT3A | P56704 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857495 | 0.91 | ALDH1A1 (0.33) | ALDH1A1LMNATP53MAPTKLF5 | |
| SCHEMBL13987983 | 0.80 | NPSR1 (0.47) | ALDH1A1MAPTSMN1; SMN2USP2KMT2A | |
| SCHEMBL13988024 | 0.80 | HTR1A (0.43) | HDAC3HDAC1HDAC2 | |
| SCHEMBL13988010 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2USP2KMT2A | |
| SCHEMBL4860892 | 0.79 | ALDH1A1 (0.37) | CTNNB1WNT3AALDH1A1LMNATP53 | |
| SCHEMBL13988041 | 0.78 | CYP11B1 (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL13988032 | 0.78 | HDAC1 (0.33) | CTNNB1WNT3AALDH1A1USP2HPGD | |
| SCHEMBL13988027 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNATP53MAPTSMN1; SMN2 | |
| SCHEMBL13988037 | 0.75 | HDAC1 (0.32) | L3MBTL1HSP90AA1HSP90AB1HDAC3HDAC1 | |
| SCHEMBL4857629 | 0.74 | CTNNB1 (0.49) | CTNNB1WNT3AALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |