SCHEMBL4857629

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4860588	0.88	CTNNB1 (0.57)	CTNNB1WNT3AACHESMN1; SMN2ALDH1A1
	SCHEMBL4853308	0.85	PTGS1 (0.33)	CTNNB1WNT3ANPC1RAB9AGRM1
	SCHEMBL4857495	0.84	ALDH1A1 (0.33)	ACHESMN1; SMN2ALDH1A1TDP1L3MBTL1
	SCHEMBL4860213	0.81	CASP3 (0.50)	SMN1; SMN2ALDH1A1L3MBTL1LMNAMAPT
	SCHEMBL4861199	0.80	MCHR1 (0.38)	ACHELMNA
	SCHEMBL4856265	0.80	HTR1A (0.42)	ACHEALDH1A1
	SCHEMBL4851911	0.80	PTGS1 (0.38)	NPC1RAB9A
	SCHEMBL4859795	0.80	CASP3 (0.49)	SMN1; SMN2ALDH1A1L3MBTL1LMNAMAPT
	SCHEMBL4861390	0.80	MCHR1 (0.43)	SMN1; SMN2ALDH1A1LMNAMAPTHPGD
	SCHEMBL4861603	0.80	NPC1 (0.47)	ACHENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.