Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856265 | 0.91 | HTR1A (0.42) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL4852226 | 0.90 | ACHE (0.42) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL4861872 | 0.90 | MAOA (0.47) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL13987983 | 0.84 | NPSR1 (0.47) | — | |
| SCHEMBL13988041 | 0.83 | CYP11B1 (0.36) | DRD2GRIN2B | |
| SCHEMBL13988010 | 0.83 | ALDH1A1 (0.48) | — | |
| SCHEMBL13988032 | 0.81 | HDAC1 (0.33) | HDAC3HDAC1HDAC2 | |
| SCHEMBL13988043 | 0.80 | CTNNB1 (0.35) | HDAC3HDAC1HDAC2 | |
| SCHEMBL4851846 | 0.80 | DRD3 (0.44) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL4858283 | 0.78 | HTR1A (0.46) | HTR1AHTR2AHTR7DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |