Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 14/20 | 0.58 |
| ▸ | CA12 | O43570 | 13/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.58 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.58 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.58 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.58 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 9/20 | 0.58 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.51 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.51 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.51 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BMP1 | P13497 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873867 | 0.86 | CA9 (0.55) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL14349177 | 0.85 | HTT (0.66) | RAB9ASMN1; SMN2ABCC9ABCC8KCNJ11 | |
| SCHEMBL12169380 | 0.85 | ALDH1A1 (0.47) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL12169361 | 0.84 | ALDH1A1 (0.47) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL3685046 | 0.83 | HCRTR2 (0.44) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| Ditolamide SCHEMBL2110790 | 0.79 | CA9 (0.64) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL24961912 | 0.79 | ABCC9 (0.59) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL12169390 | 0.78 | TDP1 (0.46) | SMN1; SMN2MEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL4081266 | 0.78 | CA9 (0.62) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL24162488 | 0.78 | KMT2A (0.74) | CA9CA12CA2RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312435-A1 | Imine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312435-A1 | Imine Compound | CNR1, CNR2, HRH4 | CA9 635/4885CA12 1663/4885CA2 1125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.