Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 14/20 | 0.55 |
| ▸ | CA12 | O43570 | 13/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.55 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.55 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.55 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 10/20 | 0.55 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.49 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13990652 | 0.86 | CA9 (0.58) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL414560 | 0.79 | CA9 (0.62) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL23536128 | 0.77 | LMNA (0.52) | CA9CA12CA2SMN1; SMN2CA1 | |
| Ditolamide SCHEMBL2110790 | 0.77 | CA9 (0.64) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL24961912 | 0.76 | ABCC9 (0.59) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL4081266 | 0.75 | CA9 (0.62) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL2932532 | 0.75 | CA9 (0.62) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL24162488 | 0.75 | KMT2A (0.74) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL28808612 | 0.75 | CA9 (0.62) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL13990835 | 0.75 | CA9 (0.62) | CA9CA12CA2RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-5780642-A | NON-STEROIDAL ANTIINFLAMMATORY AGENT WHICH BLOCKS RELEASE OF ARACHIDONIC ACID FROM PHOSPHOLIPIDS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |