Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | F7 | P08709 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | F3 | P13726 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13991881 | 0.84 | EPHX2 (0.44) | PLA2G4APLA2G2AEPHX2ALDH1A1OXER1 | |
| SCHEMBL13991902 | 0.79 | EPHX2 (0.39) | PLA2G4APLA2G2AEPHX2ALDH1A1KMT2A | |
| SCHEMBL13286572 | 0.78 | PLA2G4A (0.68) | PLA2G4APLA2G2AEPHX2ALDH1A1KMT2A | |
| SCHEMBL2770529 | 0.72 | PLA2G4A (1.00) | PLA2G4APLA2G2AEPHX2ALDH1A1KMT2A | |
| SCHEMBL1877382 | 0.72 | PLA2G4A (1.00) | PLA2G4APLA2G2AEPHX2ALDH1A1KMT2A | |
| SCHEMBL4927236 | 0.72 | PLA2G4A (0.82) | PLA2G4APLA2G2AEPHX2F7CYP19A1 | |
| SCHEMBL4795104 | 0.72 | PLA2G4A (0.82) | PLA2G4APLA2G2AEPHX2F7CYP19A1 | |
| SCHEMBL21319304 | 0.71 | EPHX2 (0.78) | EPHX2ALDH1A1F7CYP19A1F3 | |
| SCHEMBL28254961 | 0.69 | PLA2G4A (0.55) | PLA2G4APLA2G2AEPHX2LMNA | |
| Valeric Acid SCHEMBL28842310 | 0.69 | AKR1B1 (0.64) | ALDH1A1F7CYP19A1F3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319065-A1 | Systemic and Intrathecal Effects of a Novel Series of Phospholipase A2 Inhibitors on Hyperalgesia and Spinal Pge2 Release | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319065-A1 | Systemic and Intrathecal Effects of a Novel Series of Phospholipase A2 Inhibitors on Hyperalgesia and Spinal Pge2 Release | PLA2G4A, PLA2G4B, PLA2G2A | PLA2G4A 1/4885PLA2G2A 3/4885EPHX2 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.