Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 5/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142223 | 0.93 | SLC6A12 (0.43) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL25678378 | 0.79 | — | — | |
| SCHEMBL1861904 | 0.79 | — | — | |
| SCHEMBL12993394 | 0.79 | — | — | |
| SCHEMBL17281763 | 0.78 | SLC6A12 (0.41) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL9278180 | 0.75 | SLC6A12 (0.57) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL6427735 | 0.75 | SLC6A12 (0.43) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL17755669 | 0.72 | ALOX5 (0.39) | — | |
| SCHEMBL13992034 | 0.72 | GBA1 (0.32) | — | |
| SCHEMBL1927992 | 0.72 | HSD11B1 (0.44) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318188-A1 | Dimer Acid-Derived Dimethacrylates and Use in Dental Restorative Compositions | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318188-A1 | Dimer Acid-Derived Dimethacrylates and Use in Dental Restorative Compositions | GRM7, NR2C2, GRM8 | SLC6A12 4011/4885SLC6A11 4051/4885SLC6A13 3242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.