Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27168282 | 0.86 | PGR (0.50) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL13993964 | 0.81 | PGR (0.45) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL529713 | 0.80 | SIGMAR1 (0.48) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL13994249 | 0.79 | ADRA2B (0.46) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL16656809 | 0.77 | ALOX5 (0.52) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL27168281 | 0.72 | ALOX5 (0.47) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Isopropylbenzene SCHEMBL27508655 | 0.72 | CRHBP (0.56) | LMNASMN1; SMN2CYP2D6ALDH1A1MAPT | |
| SCHEMBL29582293 | 0.72 | TP53 (0.48) | ALOX5SMN1; SMN2CYP2D6ALDH1A1MAPT | |
| SCHEMBL2479871 | 0.72 | ALOX5 (0.50) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL15131012 | 0.72 | HRH1 (0.57) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462592-B2 | Compositions and methods for polynucleotide delivery | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2008-12-09 | — | — | US | disclosed |