Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310818 | 0.77 | ALDH1A1 (0.42) | ALOX15TDP1 | |
| SCHEMBL30694966 | 0.60 | TDP2 (0.58) | ALOX15TDP1 | |
| SCHEMBL311088 | 0.60 | TDP2 (0.58) | ALOX15TDP1 | |
| SCHEMBL7851288 | 0.60 | KDM4E (0.33) | — | |
| SCHEMBL9357079 | 0.59 | MAPT (0.52) | ALOX15TDP1 | |
| SCHEMBL4071878 | 0.59 | CDC25B (0.47) | ALOX15TDP1 | |
| Phthalic Anhydride SCHEMBL410690 | 0.57 | TDP1 (0.48) | ALOX15TDP1 | |
| SCHEMBL7811318 | 0.53 | TDP1 (0.50) | ALOX15TDP1 | |
| SCHEMBL3993249 | 0.52 | TDP1 (0.59) | ALOX15TDP1 | |
| SCHEMBL28539170 | 0.52 | ALOX15 (0.50) | ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318964-A1 | DEUTERIUM-ENRICHED ESZOPICLONE | PROTIA, LLC (US) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318964-A1 | DEUTERIUM-ENRICHED ESZOPICLONE | CYP27B1, CYP24A1, HSD11B2 | ALOX15 2072/4885TDP1 4504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.