Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.66 |
| ▸ | MEN1 | O00255 | 11/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.66 |
| ▸ | HTT | P42858 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | CCR6 | P51684 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14438981 | 0.76 | MEN1 (0.78) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL13942699 | 0.75 | KMT2A (0.77) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL12717683 | 0.72 | MAPT (0.87) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL13576487 | 0.71 | LMNA (0.81) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL30784990 | 0.70 | HRH4 (0.57) | MAPTMEN1KMT2AHTTBLM | |
| SCHEMBL22737353 | 0.69 | MAPT (0.68) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL13091227 | 0.68 | MAPT (0.61) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL13944051 | 0.67 | LMNA (0.70) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL23345487 | 0.67 | MEN1 (0.71) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL14502988 | 0.67 | MEN1 (0.83) | MAPTMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080305102-A1 | Therapeutic Agent for Cancer Comprising Substance Capable of Inhibiting Expression or Function of Synoviolin as Active Ingredient and Screening Method for the Therapeutic Agent for Cancer | LOCOMOGENE, INC. (JP) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305102-A1 | Therapeutic Agent for Cancer Comprising Substance Capable of Inhibiting Expression or Function of Synoviolin as Active Ingredient and Screening Method for the Therapeutic Agent for Cancer | SYVN1, TP53, UBQLN1 | MAPT 3966/4885MEN1 3843/4885KMT2A 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.