Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012548 | 0.80 | CYP2C9 (0.54) | HTTCYP2C9MAPK1ALDH1A1KDM4E | |
| SCHEMBL15694845 | 0.79 | HTT (0.59) | HTTCYP2C9MAPK1ALDH1A1KDM4E | |
| SCHEMBL13997137 | 0.78 | HTT (0.55) | HTTCYP2C9MAPK1ALDH1A1KDM4E | |
| SCHEMBL5010847 | 0.78 | HTT (0.51) | HTTCYP2C9MAPK1ALDH1A1KDM4E | |
| SCHEMBL5010875 | 0.76 | MAPK1 (0.59) | HTTCYP2C9MAPK1ALDH1A1KDM4E | |
| SCHEMBL14280209 | 0.75 | HTT (0.55) | HTTCYP2C9MAPK1ALDH1A1KDM4E | |
| SCHEMBL12345589 | 0.75 | HTT (0.59) | HTTCYP2C9MAPK1ALDH1A1KDM4E | |
| SCHEMBL5605369 | 0.73 | APP (0.64) | HTTCYP2C9MAPK1ALDH1A1KDM4E | |
| SCHEMBL445355 | 0.73 | ALDH1A1 (0.48) | HTTCYP2C9MAPK1ALDH1A1KDM4E | |
| SCHEMBL20130358 | 0.73 | TSHR (0.53) | HTTCYP2C9MAPK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389626-B1 | Aromatic copolymers of pyrroles and an electroluminescent element using the same | KOREA INST SCI & TECH (KR) | 2008-12-31 | — | — | EP | disclosed |