Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28517963 | 0.91 | DHODH (0.39) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL10028781 | 0.91 | NTRK1 (0.35) | KMT2AMEN1NTRK1MALT1DHODH | |
| SCHEMBL10028759 | 0.86 | CHIA (0.40) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL11893200 | 0.86 | DHODH (0.37) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL782242 | 0.85 | MALT1 (0.38) | KMT2ANTRK1MALT1DHODHTRPV1 | |
| SCHEMBL28455374 | 0.83 | DHODH (0.40) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL782499 | 0.83 | CNR1 (0.36) | ALDH1A1KMT2AMAPTHPGDMALT1 | |
| SCHEMBL13998590 | 0.83 | F10 (0.43) | KMT2AMEN1NTRK1 | |
| SCHEMBL10028783 | 0.82 | DHODH (0.41) | ALDH1A1KMT2AMEN1NTRK1MALT1 | |
| SCHEMBL950260 | 0.81 | DHODH (0.41) | KMT2ANTRK1MALT1DHODHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1686857-B1 | COMBINATION OF ACTIVE SUBSTANCES WITH INSECTICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2008-12-10 | — | — | EP | disclosed |