Sugi Predict

Sugi Predict / Compounds / SCHEMBL782499

SCHEMBL782499

SCHEMBL782499

CC(C)NC(=O)c1cc(Cl)cc(Cl)c1NC(=O)c1cc(Cl)nn1-c1ncccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 3/20 0.36
▸ CNR2 P34972 3/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ PKM P14618 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ CAPN1 P07384 1/20 0.35
▸ RECQL P46063 1/20 0.35
▸ TSHR P16473 1/20 0.34
▸ PDE4A P27815 2/20 0.34
▸ KCNH2 Q12809 2/20 0.34
▸ RBP4 P02753 1/20 0.34
▸ ALPL P05186 1/20 0.34
▸ DHODH Q02127 1/20 0.34
▸ MALT1 Q9UDY8 1/20 0.33
▸ KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10140225 0.93 CNR1 (0.37) CNR1CNR2ALDH1A1POLBMAPT
SCHEMBL15693411 0.93 DHODH (0.33) CAPN1KCNH2RBP4DHODHMALT1
SCHEMBL782483 0.93 MALT1 (0.37) CNR1CNR2ALDH1A1POLBMAPT
SCHEMBL31256508 0.91 DHODH (0.41) CNR1CNR2ALDH1A1POLBMAPT
SCHEMBL782468 0.91 DHODH (0.41) CNR1CNR2ALDH1A1POLBMAPT
SCHEMBL782242 0.89 MALT1 (0.38) RBP4DHODHMALT1KMT2A
SCHEMBL15743795 0.88 CAPN1 (0.34) CNR1CNR2ALDH1A1POLBMAPT
SCHEMBL782369 0.88 PDE4B (0.37) ALDH1A1MAPTDHODHKMT2A
SCHEMBL11893200 0.88 DHODH (0.37) ALDH1A1MAPTHPGDRBP4DHODH
SCHEMBL3196343 0.87 CNR1 (0.33) CNR1CNR2ALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210378242-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2021-12-09 — — US disclosed
US-10405548-B2 Fungicidal compositions SYNGENTA CROP PROTECTION LLC (US) 2019-09-10 — — US disclosed
US-9949482-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, LLC (US) 2018-04-24 — — US disclosed
US-9771365-B2 Spiroheterocyclic N-oxypiperidines as pesticides SYNGENTA PARTICIPATIONS AG (CH) 2017-09-26 — — US disclosed
US-9771365-B2 Spiroheterocyclic N-oxypiperidines as pesticides SYNGENTA PARTICIPATIONS AG (CH) 2017-09-26 — — US disclosed
US-20170071205-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2017-03-16 — — US disclosed
US-20170027173-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, LLC (US) 2017-02-02 — — US disclosed
US-20170027173-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, LLC (US) 2017-02-02 — — US disclosed
EP-2723723-B1 N-OXY PYRAZOLO-TRIAZEPINE-DIONE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2017-02-01 — — EP disclosed
US-9538755-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, LLC (US) 2017-01-10 — — US disclosed
US-20070244073-A1 Pesticidal Mixtures SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 — — US disclosed
US-20070244073-A1 Pesticidal Mixtures SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 — — US disclosed
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-10-04 — — US disclosed
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-10-04 — — US disclosed
WO-2007093402-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 — — WO disclosed
WO-2007080131-A2 ANTHRANILAMIDE DERIVATIVES AND THEIR USE FOR THE CONTROL OF INSECTS AND ACARI SYNGENTA PARTICIPATIONS AG (CH) 2007-07-19 — — WO disclosed
US-20070142327-A1 Active compound combinations having insecticidal properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-06-21 — — US disclosed
US-20070142327-A1 Active compound combinations having insecticidal properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-06-21 — — US disclosed
WO-2007020050-A2 BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-02-22 — — WO disclosed
WO-2007009661-A2 PESTICIDAL MIXTURES CONTAINING BICYCLIC ANTHRANILAMIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-01-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210378242-A1 FUNGICIDAL COMPOSITIONS PIK3C3, CYP51A1, CYP1B1 CNR1 3467/4885CNR2 3086/4885ALDH1A1 1601/4885
US-20070142327-A1 Active compound combinations having insecticidal properties ACHE, ANTXR2, NANP CNR1 1471/4885CNR2 1405/4885ALDH1A1 4054/4885
US-20170027173-A1 INSECTICIDAL COMPOUNDS ACHE, AADAC, CASP3 CNR1 1508/4885CNR2 1585/4885ALDH1A1 391/4885
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties ACHE, CHRM3, CHRNA2 CNR1 44/4885CNR2 43/4885ALDH1A1 2132/4885
US-20070244073-A1 Pesticidal Mixtures ACHE, ATL3, BPHL CNR1 1735/4885CNR2 1482/4885ALDH1A1 1866/4885
US-10405548-B2 Fungicidal compositions PIK3C3, CYP51A1, CYP1B1 CNR1 3467/4885CNR2 3086/4885ALDH1A1 1601/4885
US-20170071205-A1 FUNGICIDAL COMPOSITIONS PIK3C3, CYP51A1, CYP1B1 CNR1 3467/4885CNR2 3086/4885ALDH1A1 1601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.