Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12528144 | 0.94 | F10 (0.42) | F10MEN1KMT2A | |
| SCHEMBL10028781 | 0.91 | NTRK1 (0.35) | F10NTRK1MEN1KMT2A | |
| SCHEMBL10028783 | 0.90 | DHODH (0.41) | F10NTRK1MEN1KMT2A | |
| SCHEMBL12528237 | 0.89 | NTRK1 (0.39) | F10NTRK1MEN1KMT2ATSHR | |
| SCHEMBL10028786 | 0.87 | F10 (0.39) | F10MEN1KMT2A | |
| SCHEMBL12528592 | 0.84 | DHODH (0.43) | F10NTRK1MEN1KMT2A | |
| SCHEMBL950260 | 0.83 | DHODH (0.41) | NTRK1KMT2A | |
| SCHEMBL13998637 | 0.83 | ALDH1A1 (0.33) | NTRK1MEN1KMT2A | |
| SCHEMBL12911819 | 0.82 | F10 (0.38) | F10MEN1KMT2A | |
| SCHEMBL12528142 | 0.82 | KMT2A (0.40) | F10NTRK1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1686857-B1 | COMBINATION OF ACTIVE SUBSTANCES WITH INSECTICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2008-12-10 | — | — | EP | disclosed |