Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | JAK2 | O60674 | 4/20 | 0.48 |
| ▸ | JAK1 | P23458 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777892 | 0.78 | SMN1; SMN2 (0.58) | HTTNOD2KDM4EALDH1A1LMNA | |
| SCHEMBL12417622 | 0.76 | BRD4 (0.42) | HTTKDM4ENPC1RAB9A | |
| SCHEMBL12809054 | 0.76 | KDM4E (0.37) | KDM4EHIF1AGAANPC1RAB9A | |
| SCHEMBL1777177 | 0.73 | RAB9A (0.41) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL23356002 | 0.70 | CA12 (0.46) | CYP3A4KDM4EALDH1A1LMNA | |
| SCHEMBL1400324 | 0.69 | CA12 (0.57) | XDHCYP3A4KDM4EALDH1A1LMNA | |
| SCHEMBL1892848 | 0.69 | RAB9A (0.58) | HTTCYP3A4KDM4EALDH1A1LMNA | |
| SCHEMBL15708776 | 0.68 | ALDH1A1 (0.54) | HTTKDM4EALDH1A1LMNAHSP90AA1 | |
| SCHEMBL30919366 | 0.68 | ALDH1A1 (0.54) | HTTKDM4EALDH1A1LMNAHSP90AA1 | |
| SCHEMBL17013251 | 0.68 | SLC22A12 (0.68) | XDHSLC22A12TYK2HTTJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943638-B2 | Carboxamide compound and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-17 | — | — | US | disclosed |
| US-7943638-B2 | Carboxamide compound and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-17 | — | — | US | disclosed |
| US-7943638-B2 | Carboxamide compound and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-17 | — | — | US | disclosed |
| EP-1915365-B1 | CARBOXAMIDE COMPOUND AND USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2011-03-02 | — | — | EP | disclosed |
| US-20090111852-A1 | Carboxamide Compound and Use of the Same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20090111852-A1 | Carboxamide Compound and Use of the Same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20090111852-A1 | Carboxamide Compound and Use of the Same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111852-A1 | Carboxamide Compound and Use of the Same | CBR3, H1-3, H1-0 | XDH 1083/4885SLC22A12 3845/4885TYK2 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.