Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15708776 | 1.00 | ALDH1A1 (0.54) | ALDH1A1HTTLMNAALOX15HSP90AA1 | |
| SCHEMBL30919377 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HTTLMNAALOX15HSP90AA1 | |
| SCHEMBL20869628 | 0.84 | MAPT (0.51) | ALDH1A1HTTLMNAALOX15HSP90AA1 | |
| SCHEMBL15709084 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HTTLMNAALOX15HSP90AA1 | |
| SCHEMBL8999141 | 0.80 | NPC1 (0.80) | ALDH1A1HTTLMNAALOX15HSP90AA1 | |
| SCHEMBL8998915 | 0.79 | SRC (0.81) | ALDH1A1NPC1EGFRSRCFGFR1 | |
| Pyridine SCHEMBL10677617 | 0.76 | NPC1 (0.69) | ALDH1A1HTTLMNAALOX15HSP90AA1 | |
| SCHEMBL15797031 | 0.75 | NPC1 (0.61) | ALDH1A1HTTNPC1EGFRSRC | |
| SCHEMBL30919342 | 0.72 | SLC22A12 (0.58) | HTTALOX15HSP90AA1HIF1ANPC1 | |
| SCHEMBL15709042 | 0.72 | SLC22A12 (0.58) | HTTALOX15HSP90AA1HIF1ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11975032-B2 | Medicament for liver regeneration and for treatment of liver failure | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2024-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11975032-B2 | Medicament for liver regeneration and for treatment of liver failure | PYGL, HNF4A, ATF1 | ALDH1A1 1437/4885HTT 4857/4885LMNA 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.