Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.37 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14000133 | 0.85 | GUCY1A1 (0.51) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL18622661 | 0.75 | FERMT2 (0.50) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL16502278 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL14000123 | 0.74 | GAA (0.49) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL13999724 | 0.74 | MAOA (0.39) | ALDH1A1MAPTPKM | |
| SCHEMBL14000124 | 0.74 | MAOA (0.39) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8720521 | 0.73 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL29836137 | 0.72 | ICMT (0.39) | ALDH1A1MAPTPKM | |
| SCHEMBL2755845 | 0.72 | MAPT (0.54) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL13999720 | 0.71 | MAOA (0.39) | MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009005-A1 | AZOLECARBOXAMIDE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |