Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003922 | 0.87 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13805530 | 0.87 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14003924 | 0.83 | KIF11 (0.46) | KIF11ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL14003929 | 0.83 | KIF11 (0.46) | KIF11ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL14003930 | 0.81 | RXFP1 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14374020 | 0.78 | KIF11 (0.40) | KIF11ALDH1A1MAPTKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL9536911 | 0.77 | ESR1 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14374011 | 0.73 | KIF11 (0.43) | KIF11DRD1ALDH1A1MAPTKDM4E | |
| SCHEMBL2069242 | 0.72 | KIF11 (0.47) | KIF11ALDH1A1HSD17B10TP53ALOX15 | |
| SCHEMBL14003927 | 0.71 | RXFP1 (0.51) | ALDH1A1MAPTKDM4EHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080286219-A1 | Hydroquinone derivative skin brightening compounds | EASTMAN CHEMICAL COMPANY | 2008-11-20 | — | — | US | disclosed |
| US-20080286219-A1 | Hydroquinone derivative skin brightening compounds | EASTMAN CHEMICAL COMPANY | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080286219-A1 | Hydroquinone derivative skin brightening compounds | NQO1, CUTA, TYR | CA12 3932/4885CA1 4807/4885CA2 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.