Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MARS1 | P56192 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HK2 | P52789 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14374010 | 0.76 | ALDH1A1 (0.45) | ALDH1A1GAAGFERKDM4ECYP3A4 | |
| SCHEMBL14003928 | 0.73 | CA12 (0.41) | KIF11DRD1ALDH1A1MARS1GAA | |
| SCHEMBL14347057 | 0.73 | ALOX5 (0.41) | PTGS2TRPV1 | |
| SCHEMBL15700636 | 0.73 | KIF11 (0.40) | KIF11DRD1ALDH1A1IDO1 | |
| SCHEMBL14347058 | 0.72 | KIF11 (0.38) | KIF11DRD1ALDH1A1MARS1GAA | |
| Hydrochloric Acid SCHEMBL9536911 | 0.71 | ESR1 (0.43) | KIF11DRD1ESR2ESR1MMP2 | |
| SCHEMBL2951317 | 0.70 | KIF11 (0.55) | KIF11CYP3A4KMT2A | |
| SCHEMBL10977541 | 0.70 | KIF11 (0.55) | KIF11CYP3A4KMT2A | |
| SCHEMBL14374020 | 0.70 | KIF11 (0.40) | KIF11ALDH1A1MARS1KDM4ECYP3A4 | |
| Hydrochloric Acid SCHEMBL3610043 | 0.69 | KIF11 (0.53) | KIF11CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070286906-A1 | DIHYDROBENZOQUINONE COMPOUNDS | HUTCHISON MEDIPHARMA ENTERPRISES LIMITED (BS) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070286906-A1 | DIHYDROBENZOQUINONE COMPOUNDS | NQO1, SDHA, SDHB | KIF11 1812/4885DRD1 1138/4885ALDH1A1 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.