Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MARS1 | P56192 | 5/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003928 | 0.78 | CA12 (0.41) | KIF11ALDH1A1MARS1LMNAKDM4E | |
| SCHEMBL14347058 | 0.77 | KIF11 (0.38) | KIF11ALDH1A1MARS1LMNAHSD17B2 | |
| SCHEMBL14374015 | 0.76 | HSD17B10 (0.48) | ALDH1A1LMNAHMGCRKDM4ECYP3A4 | |
| SCHEMBL14347054 | 0.72 | ALOX5 (0.55) | — | |
| SCHEMBL6384400 | 0.70 | ALDH1A1 (0.61) | ALDH1A1MARS1LMNAHSD17B2KDM4E | |
| SCHEMBL14374011 | 0.70 | KIF11 (0.43) | KIF11ALDH1A1MARS1MMP2MMP9 | |
| SCHEMBL2069242 | 0.68 | KIF11 (0.47) | KIF11ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL11348840 | 0.67 | BLM (0.58) | MMP2MMP9MMP8MMP13LMNA | |
| Hydrochloric Acid SCHEMBL9536911 | 0.67 | ESR1 (0.43) | KIF11MMP2MMP9MMP13 | |
| SCHEMBL111172 | 0.66 | KIF11 (0.43) | KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070286906-A1 | DIHYDROBENZOQUINONE COMPOUNDS | HUTCHISON MEDIPHARMA ENTERPRISES LIMITED (BS) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070286906-A1 | DIHYDROBENZOQUINONE COMPOUNDS | NQO1, SDHA, SDHB | KIF11 1812/4885ALDH1A1 122/4885MARS1 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.