SCHEMBL14005673

SCHEMBL14005673

CC1OC(COC(=O)c2ccccc2)C(OC(=O)c2ccccc2)C(OC(=O)c2ccccc2)C1OC(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.54
POLB P06746 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
PTPN1 P18031 4/20 0.49
TSHR P16473 1/20 0.49
ALDH1A1 P00352 1/20 0.48
F11 P03951 2/20 0.47
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 1/20 0.46
GAPDH P04406 2/20 0.46
ELANE P08246 1/20 0.46
MAPK1 P28482 2/20 0.45
TMPRSS2 O15393 1/20 0.45
PDE5A O76074 1/20 0.45
HMGCR P04035 1/20 0.45
CYP1A2 P05177 1/20 0.45
LCK P06239 1/20 0.45
FYN P06241 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24378511 1.00 USP2 (0.54) USP2POLBMEN1KMT2APTPN1
SCHEMBL20739194 1.00 USP2 (0.54) USP2POLBMEN1KMT2APTPN1
SCHEMBL23895306 1.00 USP2 (0.54) USP2POLBMEN1KMT2APTPN1
SCHEMBL12300564 0.99 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL21754836 0.99 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL12222446 0.99 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL21754881 0.99 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL15759263 0.99 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL18871302 0.99 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL25506254 0.99 USP2 (0.55) USP2POLBMEN1KMT2APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134986-A1 GLUCOSE TRIPTOLIDE CONJUGATES AND USES THEREOF SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2023-05-04 US disclosed
EP-3141265-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES Alnylam Pharmaceuticals, Inc. (US) 2017-03-15 EP disclosed
WO-2011127180-A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF CD274/PD-L1 GENE ALNYLAM PHARMACEUTICALS, INC. (US) 2011-10-13 WO disclosed
US-20080275225-A1 Synthetic Method of 20 (S)-Ginsenoside Rh2 SHANGHAI INNIVATIVE RESEARCH CENTER OF TRADITIONAL (CN) 2008-11-06 US disclosed
US-20080171706-A1 Anti-Adhesive Compounds to Prevent and Treat Bacterial Infections VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW (BE) 2008-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230134986-A1 GLUCOSE TRIPTOLIDE CONJUGATES AND USES THEREOF SLC2A1, SLC2A9, GID4 USP2 1955/4885POLB 3826/4885MEN1 3088/4885
US-20080171706-A1 Anti-Adhesive Compounds to Prevent and Treat Bacterial Infections EPCAM, ICAM1, CDH1 USP2 2700/4885POLB 3062/4885MEN1 2598/4885
US-20080275225-A1 Synthetic Method of 20 (S)-Ginsenoside Rh2 RPN2, DDOST, MRPS22 USP2 3506/4885POLB 4130/4885MEN1 2341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.