Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 5/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18065729 | 0.85 | LOXL2 (0.51) | LOXL2ALDH1A1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL30073068 | 0.82 | CHRM2 (0.49) | ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5738287 | 0.80 | MEN1 (0.59) | ALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL3026173 | 0.78 | MEN1 (0.57) | ALDH1A1ATM | |
| SCHEMBL7023370 | 0.78 | ENPP2 (0.47) | LOXL2NOS2NOS1ALDH1A1NOS3 | |
| SCHEMBL21799942 | 0.78 | CYP1A2 (0.49) | LOXL2NOS2NOS1ALDH1A1NOS3 | |
| SCHEMBL30219100 | 0.78 | MC4R (0.58) | LOXL2CYP1A2CYP2D6CYP2C19ENPP2 | |
| SCHEMBL21498145 | 0.78 | TPSAB1 (0.60) | NOS2CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13206793 | 0.78 | TPSAB1 (0.60) | NOS2CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14007283 | 0.77 | LTA4H (0.46) | LOXL2ALDH1A1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287644-A1 | HARDENER FOR EPOXY RESINS, METHOD FOR HARDENING AN EPOXY RESIN AND USE OF THE HARDENER | UPPC AG (DE) | 2008-11-20 | — | — | US | disclosed |