SCHEMBL14008303

SCHEMBL14008303

Cc1ccc(-c2oc3cc(O)cc(O)c3c(=O)c2O)c(O)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 8/20 0.78
▸ KMT2A Q03164 8/20 0.78
▸ XDH P47989 7/20 0.78
▸ CYP3A4 P08684 6/20 0.78
▸ CYP2C9 P11712 6/20 0.78
▸ FTO Q9C0B1 6/20 0.78
▸ APP P05067 5/20 0.78
▸ MAPT P10636 5/20 0.78
▸ KDM4E B2RXH2 5/20 0.78
▸ ALOX15 P16050 5/20 0.78
▸ HSD17B10 Q99714 5/20 0.78
▸ ALDH1A1 P00352 4/20 0.78
▸ HPGD P15428 4/20 0.78
▸ CSNK2A2 P19784 4/20 0.78
▸ DAPK1 P53355 4/20 0.78
▸ BACE1 P56817 4/20 0.78
▸ CSNK2B P67870 4/20 0.78
▸ CSNK2A1 P68400 4/20 0.78
▸ GLO1 Q04760 4/20 0.78
▸ CSNK2A3 Q8NEV1 4/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31424112 0.91 APP (0.70) MEN1KMT2AXDHCYP3A4CYP2C9
Morin SCHEMBL10335390 0.88 MEN1 (1.00) MEN1KMT2AXDHCYP3A4CYP2C9
Morin SCHEMBL29435805 0.88 MEN1 (1.00) MEN1KMT2AXDHCYP3A4CYP2C9
Morin SCHEMBL19984 0.88 MEN1 (1.00) MEN1KMT2AXDHCYP3A4CYP2C9
Morin SCHEMBL29929115 0.88 MEN1 (1.00) MEN1KMT2AXDHCYP3A4CYP2C9
Morin SCHEMBL294933 0.87 MPG (1.00) MEN1KMT2AXDHCYP3A4CYP2C9
Morin SCHEMBL7116848 0.87 MPG (1.00) MEN1KMT2AXDHCYP3A4CYP2C9
Morin SCHEMBL21874430 0.87 MEN1 (0.97) MEN1KMT2AXDHCYP3A4CYP2C9
Morin SCHEMBL15106661 0.87 MPG (1.00) MEN1KMT2AXDHCYP3A4CYP2C9
Morin SCHEMBL29400568 0.87 MPG (1.00) MEN1KMT2AXDHCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11744820-B2 Inhibitors of microbially induced amyloid AXIAL THERAPEUTICS, INC. (US) 2023-09-05 — — US disclosed
US-20170107242-A1 NOVEL FLAVONOIDS O-A-GLUCOSYLATED ON THE B CYCLE, METHOD FOR THE PRODUCTION THEREOF AND USES INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) 2017-04-20 — — US disclosed
US-20080292566-A1 ORAL COMPOSITION CONTAINING MORIN COLGATE-PALMOLIVE COMPANY (US) 2008-11-27 — — US disclosed
US-20070092454-A1 Oral composition containing morin COLGATE-PALMOLIVE COMPANY 2007-04-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170107242-A1 NOVEL FLAVONOIDS O-A-GLUCOSYLATED ON THE B CYCLE, METHOD FOR THE PRODUCTION THEREOF AND USES UGGT1, ENGASE, OGA MEN1 4032/4885KMT2A 3812/4885XDH 680/4885
US-20080292566-A1 ORAL COMPOSITION CONTAINING MORIN LPO, MB, HMOX2 MEN1 2961/4885KMT2A 3164/4885XDH 440/4885
US-11744820-B2 Inhibitors of microbially induced amyloid APP, PSEN1, BACE1 MEN1 3857/4885KMT2A 4653/4885XDH 523/4885
US-20070092454-A1 Oral composition containing morin LPO, MB, HMOX2 MEN1 2961/4885KMT2A 3164/4885XDH 440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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